Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | BreastCancer Custom__BreastCancer_custom-females- |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | CL34187, DESMOSOME, AND ICHTHYOSIS VULGARIS |
| Enrichment Score (ES) | 0.4377624 |
| Normalized Enrichment Score (NES) | 0.9866791 |
| Nominal p-value | 0.5300601 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | FLG2 | 438 | 1.606 | 0.1158 | Yes |
| 2 | TMEM43 | 561 | 1.480 | 0.2383 | Yes |
| 3 | PKP1 | 1722 | 0.931 | 0.2550 | Yes |
| 4 | DSG3 | 1745 | 0.925 | 0.3345 | Yes |
| 5 | KRT2 | 2282 | 0.803 | 0.3748 | Yes |
| 6 | PPL | 2886 | 0.699 | 0.4023 | Yes |
| 7 | FLG | 3261 | 0.644 | 0.4378 | Yes |
| 8 | SERPINB12 | 4979 | 0.470 | 0.3833 | No |
| 9 | DSC2 | 5104 | 0.459 | 0.4165 | No |
| 10 | PKP2 | 6087 | 0.387 | 0.3957 | No |
| 11 | DSG2 | 7182 | 0.325 | 0.3632 | No |
| 12 | DSP | 7659 | 0.301 | 0.3631 | No |
| 13 | KRT10 | 8556 | 0.265 | 0.3364 | No |
| 14 | PKP3 | 9083 | 0.242 | 0.3283 | No |
| 15 | KRT77 | 9144 | 0.240 | 0.3459 | No |
| 16 | PERP | 9447 | 0.230 | 0.3492 | No |
| 17 | EVPL | 9798 | 0.218 | 0.3487 | No |
| 18 | CDSN | 9963 | 0.212 | 0.3581 | No |
| 19 | LORICRIN | 10319 | 0.200 | 0.3559 | No |
| 20 | CASP14 | 10374 | 0.198 | 0.3702 | No |
| 21 | JUP | 10597 | 0.192 | 0.3746 | No |
| 22 | BLMH | 11645 | 0.162 | 0.3305 | No |
| 23 | KRT1 | 12678 | 0.135 | 0.2849 | No |
| 24 | DSC1 | 14926 | 0.089 | 0.1677 | No |
| 25 | DSG1 | 16707 | 0.042 | 0.0723 | No |
| 26 | DSC3 | 17307 | -0.000 | 0.0390 | No |
